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Beilstein J. Org. Chem. 2016, 12, 2032–2037, doi:10.3762/bjoc.12.191
Graphical Abstract
Scheme 1: N-Arylepoxyisoindolines via tandem Ugi–Smiles/IMDA reaction.
Scheme 2: Reaction monitoring by 1H NMR for production of 1b.
Scheme 3: Use of a thienyl-substituted aldehyde for Ugi–Smiles couplings.